Synthesis of Arylboronic Acid Ester

General Procedure for the Synthesis of Arylboronic acid ester from Arylboroic Acid with 2,2-Dimethyl-1,3-propanediol (5 mmol scale).

In a 50ml flask equipped with a stir-bar, arylboroic acid (5 mmol) and 2,2-dimethyl-1,3-propanediol (6 mmol) were combined. 15 mL dimethyl ether was added to the flask and the solution was stirred for 6 hours under room temperature. The dimethyl ether was then removed under vacuum to get the white solid mixture. The mixture was washed three times with water to remove the excess 2,2-dimethyl-1,3-propanediol. The product was dried at 50 ℃ under vacuum.

This method gave quantitative yield for 3 g scale.