Palladium-Catalyzed C−H Aminations of Anilides with N-Fluorobenzenesulfonimide

The first amide-directed, palladium-catalyzed, intermolecular, highly selective C−H aminations with the non-nitrene-based nitrogen source N-fluorobenzenesulfonimide have been developed. This methodology might provide a new pathway for directed metal-catalyzed aromatic C−H amination.



J. Am. Chem. Soc, 2011, 133, 1694