Easy access too-acyl acetanilides: A new Pd-catalyzed ortho-acylation of acetanilides with both aromatic and aliphatic aldehydes has been developed based on a C![[BOND]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vzmfNw_7CpOM48iv41QDRMa8EyIwnBFS4LlJq3pKkRdAla3vPVx_wizW66_hcqytuaz9eyMmUDxZW9tdFbSMjgxskxiFQU14fbm9jdxrelli6MoYWjmVIBG6QMe5O0wzcxf8yQZVbeET50Lw=s0-d)
H activation process. In the presence of tert-butyl hydroperoxide (TBHP) as the ideal oxidant, this reaction provides an efficient access to ortho-acyl acetanilides in good yields (see scheme).
Chem. Eur. J, 2011, DOI: 10.1002/chem.201101192
H activation process. In the presence of tert-butyl hydroperoxide (TBHP) as the ideal oxidant, this reaction provides an efficient access to ortho-acyl acetanilides in good yields (see scheme).Chem. Eur. J, 2011, DOI: 10.1002/chem.201101192
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