Wednesday, July 25, 2012

Highly regioselective synthesis of aryl chalcogenides through C–H functionalization of arenes

We report here the regioselective synthesis of aryl chalcogenides through the iridium-catalyzedmeta C–H borylation followed by copper-catalyzed C–S coupling reaction with chalcogenide sources in one pot, giving the 3,5-disubstituted aryl chalcogenides with high regioselectivity and good yields.

Graphical abstract: Highly regioselective synthesis of aryl chalcogenides through C–H functionalization of arenes


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