An efficient and clean method to construct C![[BOND]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_uNNzKL4x73XovxQNMWGOcRdCsOMNXmAXLA1aatONvdR9ADkqvSqd7DxqRJvVRRjd76kF8FlFipmizwRCycxCv0ivNqk1YxKNSlY300pVIiIejXGAzoBWgVdZkOQ41yavtH6kr0xGVq-j3KJA=s0-d)
C bonds has been developed via the acylation reaction of acetanilides with benzylic alcohols using tert-butyl hydroperoxide (TBHP) as oxidant catalyzed by palladium acetate in the presence of triflic acid (TfOH). The acylation reactions exhibit excellent reactivities, and up to 95% yield of the corresponding aryl ketone could be obtained under the optimal conditions.
C bonds has been developed via the acylation reaction of acetanilides with benzylic alcohols using tert-butyl hydroperoxide (TBHP) as oxidant catalyzed by palladium acetate in the presence of triflic acid (TfOH). The acylation reactions exhibit excellent reactivities, and up to 95% yield of the corresponding aryl ketone could be obtained under the optimal conditions.
DOI: 10.1002/adsc.201100417
No comments:
Post a Comment