An efficient and clean method to construct C![[BOND]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tBvnDX5cUXTp70m2a815VbDPhTJBg7YP-HgJ4v8GA48OwXeBZQXm_fA0UEIHbhNs5nRo-L8KV1WJIs4ugrVdNvhasGMnW3XSX9rIdR-hw74LbtSXdUES8QX4v4C_xjqOUEKPk7zi08XMdOMA=s0-d)
C bonds has been developed via the acylation reaction of acetanilides with benzylic alcohols using tert-butyl hydroperoxide (TBHP) as oxidant catalyzed by palladium acetate in the presence of triflic acid (TfOH). The acylation reactions exhibit excellent reactivities, and up to 95% yield of the corresponding aryl ketone could be obtained under the optimal conditions.
C bonds has been developed via the acylation reaction of acetanilides with benzylic alcohols using tert-butyl hydroperoxide (TBHP) as oxidant catalyzed by palladium acetate in the presence of triflic acid (TfOH). The acylation reactions exhibit excellent reactivities, and up to 95% yield of the corresponding aryl ketone could be obtained under the optimal conditions.
DOI: 10.1002/adsc.201100417
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