Copper-catalyzed decarboxylative alkenylation of sp3 C–H bonds with cinnamic acids via a radical process

Carboxylates as sources of carbon nucleophiles and electrophiles: comparison of decarboxylative and decarbonylative pathways

Fused Benzo[b]fluorenols: Palladium-Catalyzed Intramolecular Dehydroaromatization and Carbonyl Reduction

Iron-Catalyzed Alkyl–Alkyl Suzuki–Miyaura Coupling

Synthesis of unsymmetrical biaryl ethers through nickel-promoted coupling of polyfluoroarenes with arylboronic acids and oxygen

Indium(III)-Promoted Organocatalytic Enantioselective α-Alkylation of Aldehydes with Benzylic and Benzhydrylic Alcohols

Direct Amidation of Alcohols with N-Substituted Formamides under Transition-Metal-Free Conditions

Pd-Catalyzed Modifiable Silanol-Directed Aromatic C[BOND]H Oxygenation

Fluoroform-Derived CuCF3 for Low-Cost, Simple, Efficient, and Safe Trifluoromethylation of Aryl Boronic Acids in Air

Microwave-assisted palladium mediated decarbonylation reaction: synthesis of eulatachromene

Microwave-assisted decarbonylation reactions were investigated using a palladium catalyst. A large number of aldehydes can be decarbonylated efficiently with lower catalyst loadings and under shorter reaction times compared to conventional heating. A successful decarbonylation led to the synthesis of natural product eulatachromene in three steps starting from easily available materials.

Highly regioselective synthesis of aryl chalcogenides through C–H functionalization of arenes

We report here the regioselective synthesis of aryl chalcogenides through the iridium-catalyzedmeta C–H borylation followed by copper-catalyzed C–S coupling reaction with chalcogenide sources in one pot, giving the 3,5-disubstituted aryl chalcogenides with high regioselectivity and good yields.

An efficient copper-catalyzed formation of highly substituted pyrazoles using molecular oxygen as the oxidant

An efficient Cu-catalyzed formation of tetra-substituted pyrazoles is reported. In this atom economic process, readily available enamines and nitriles are reacted by C–C and N–N bond formation. Oxygen has been successfully used as the oxidant, which has important economic and environmental advantages. A broad scope of enamines and nitriles can be utilized in this process.

TBHP/I2-promoted oxidative coupling of acetophenones with amines at room temperature under metal-free and solvent-free conditions for the synthesis of α-ketoamides

A novel and efficient TBHP/I₂-promoted oxidative coupling reaction of acetophenones with amines for the synthesis of α-ketoamides has been developed. The reactions proceeded smoothly at room temperature under metal-free and solvent-free conditions and generated the corresponding products in good yields.

A simple and facile Heck-type arylation of alkenes with diaryliodonium salts using magnetically recoverable Pd-catalyst

The Heck-type arylation of alkenes was achieved in aqueous polyethylene glycol using a magnetically recoverable heterogenized palladium catalyst employing diaryliodonium salts under ambient conditions. The benign reaction medium and the stability of the catalyst are the salient features of this simple and facile protocol.

Iron-Catalyzed ortho Monoarylation of Benzamide Derivatives

Protodecarboxylation of benzoic acids under radical conditions

Nickel(0)/NaHMDS adduct-mediated intramolecular alkylation of unactivated arenes via a homolytic aromatic substitution mechanism

Chem. Commun., 2012,48, 8249-8251      

Copper(II)-Mediated Dehydrogenative Cross-Coupling of Heteroarenes

Catalytic Radical Cation Salt Induced Csp3–H Functionalization of Glycine Derivatives: Synthesis of Substituted Quinolines

Copper Catalyzed Oxidative Esterification of Aldehydes with Alkylbenzenes via Cross Dehydrogenative Coupling

Catalytic Coupling of Arene C–H Bonds and Alkynes for the Synthesis of Coumarins: Substrate Scope and Application to the Development of Neuroimaging Agents

Synthesis of Substituted Coumarins via Brønsted Acid Mediated Condensation of Allenes with Substituted Phenols or Anisoles

Superacid-catalyzed Friedel–Crafts cyclization of unactivated alkenes

Direct arylation of benzoxazole C–H bonds with iodobenzene diacetates

Brønsted Acid Enhanced Rhodium-Catalyzed Conjugate Addition of Aryl C[BOND]H Bonds to α,β-Unsaturated Ketones under Mild Conditions

DOI: 10.1002/chem.201201348

Iron-Catalyzed, Highly Regioselective Synthesis of α-Aryl Carboxylic Acids from Styrene Derivatives and CO2

DOI: 10.1021/ja3045053

Copper-Catalyzed Aerobic Aliphatic C–H Oxygenation Directed by an Amidine Moiety

DOI: 10.1021/ja305833a

Pd(II)-Catalyzed Ortho Trifluoromethylation of Arenes and Insights into the Coordination Mode of Acidic Amide Directing Groups

DOI: 10.1021/ja305259n

Regioselective Double Hydrophosphination of Terminal Arylacetylenes Catalyzed by an Iron Complex

DOI: 10.1021/ja304818c

Connecting Binuclear Pd(III) and Mononuclear Pd(IV) Chemistry by Pd–Pd Bond Cleavage

DOI: 10.1021/ja304401u

Metal-Free Oxidative Trifluoromethylthiolation of Terminal Alkynes with CF3SiMe3 and Elemental Sulfur

DOI: 10.1021/ja305801m

Continuous-Flow Synthesis of Monoarylated Acetaldehydes Using Aryldiazonium Salts

DOI: 10.1021/ja305660a

Iridium-Catalyzed Borylation of Secondary C–H Bonds in Cyclic Ethers

DOI: 10.1021/ja305596v

Spontaneous reduction and C–H borylation of arenes mediated by uranium(III) disproportionation

Palladium-catalysed heteroannulation of [60]fullerene with N-benzyl sulfonamides and subsequent functionalisation

Coupling of enamides with alkynes or arynes for synthesis of substituted pyridines and isoquinolines via amide activation

Retracing the evolution of monometallic ruthenium–arene catalysts for C–C bond formation

Rhodium-Catalyzed Regioselective Carboacylation of Olefins: A C[BOND]C Bond Activation Approach for Accessing Fused-Ring Systems

Catalytic Aerobic Synthesis of Aromatic Ethers from Non-Aromatic Precursors

DOI: 10.1002/anie.201200698

Cobalt-Catalyzed Direct Arylation and Benzylation by C[BOND]H/C[BOND]O Cleavage with Sulfamates, Carbamates, and Phosphates

Copper-Catalyzed Aerobic Dehydrogenative Cyclization of N-Methyl-N-phenylhydrazones: Synthesis of Cinnolines

Palladium-Catalyzed Direct Arylation of N-Heteroarenes with Arylsulfonyl Hydrazides

DOI: 10.1002/chem.201201450

Cooperative Catalysis Approach to Intramolecular Hydroacylation

DOI: 10.1021/jo300779q

Ruthenium(II)-Catalyzed sp3 C–H Bond Arylation of Benzylic Amines Using Aryl Halides

DOI: 10.1021/ol301680v

Copper-Mediated Selective Cyanation of Indoles and 2-Phenylpyridines with Ammonium Iodide and DMF

DOI: 10.1021/ol301674m

Copper(II)-Mediated Dehydrogenative Cross-Coupling of Heteroarenes

DOI: 10.1021/ol301517y

Palladium-Catalyzed, Asymmetric Mizoroki–Heck Reaction of Benzylic Electrophiles Using Phosphoramidites as Chiral Ligands

DOI: 10.1021/ja304099j

Iron-Catalyzed, Highly Regioselective Synthesis of α-Aryl Carboxylic Acids from Styrene Derivatives and CO2

DOI: 10.1021/ja3045053

Copper-catalyzed decarboxylative C(sp2)–C(sp3) coupling reactions via radical mechanism

Synthesis of Aza-Fused Polycyclic Quinolines via Double C[BOND]H Bond Activation