Bond activation in action: Unprecedented ruthenium-catalyzed oxidative annulations of alkynes through cleavage of C![[BOND]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_uNNzKL4x73XovxQNMWGOcRdCsOMNXmAXLA1aatONvdR9ADkqvSqd7DxqRJvVRRjd76kF8FlFipmizwRCycxCv0ivNqk1YxKNSlY300pVIiIejXGAzoBWgVdZkOQ41yavtH6kr0xGVq-j3KJA=s0-d)
H bonds set the stage for an efficient 1(2H)-isoquinolone synthesis with ample scope (see scheme; tAm=tert-amyl). Mechanistic studies provided strong evidence for a rate-limiting CH bond metalation through carboxylate assistance.
H bonds set the stage for an efficient 1(2H)-isoquinolone synthesis with ample scope (see scheme; tAm=tert-amyl). Mechanistic studies provided strong evidence for a rate-limiting CH bond metalation through carboxylate assistance.
No comments:
Post a Comment