Bond activation in action: Unprecedented ruthenium-catalyzed oxidative annulations of alkynes through cleavage of C![[BOND]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sPEUjHbU4v8VMjbv3hZ49_MojCajp4fb4tTxWwp8M-xo4DBsCqGhmHTIB_1byDpc828HOdnRw5Z0CW_U629YKRiFRM-wViaeq43oq0CIixO5JDHU__23zW3T2Bgmc0AZ_PBatxIDsw3B_Zzw=s0-d)
H bonds set the stage for an efficient 1(2H)-isoquinolone synthesis with ample scope (see scheme; tAm=tert-amyl). Mechanistic studies provided strong evidence for a rate-limiting CH bond metalation through carboxylate assistance.
H bonds set the stage for an efficient 1(2H)-isoquinolone synthesis with ample scope (see scheme; tAm=tert-amyl). Mechanistic studies provided strong evidence for a rate-limiting CH bond metalation through carboxylate assistance.
No comments:
Post a Comment