Tuesday, February 7, 2012

Extrusion of CO from Aryl Ketones: Rhodium(I)-Catalyzed C[BOND]C Bond Cleavage Directed by a Pyridine Group - Lei - 2012 - Angewandte Chemie International Edition - Wiley Online Library


Snipping tool: The rhodium(I)-catalyzed extrusion of carbon monoxide from biaryl ketones and alkyl/alkenyl aryl ketones was developed to produce biaryls and alkyl/alkenyl arenes, respectively, in high yields (see scheme). A wide range of functionalities are tolerated. Not only does this method provide an alternative pathway to construct useful scaffolds, but also offers a new strategy for C-C bond activation.

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