Easy access too-acyl acetanilides: A new Pd-catalyzed ortho-acylation of acetanilides with both aromatic and aliphatic aldehydes has been developed based on a C![[BOND]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vhb943WY3nexORGseebnPqAh8DEuCcBhKtGYtru6V2ePS12pr5CHRh4TYh7F2vQO6mmn6vslC9p_79Dcik8T4eOBFQQ5pbwKtHqtX7TZCe4VMxttXVbCgr6eT_zZlfDb5fojgRnPHcuozBrw=s0-d)
H activation process. In the presence of tert-butyl hydroperoxide (TBHP) as the ideal oxidant, this reaction provides an efficient access to ortho-acyl acetanilides in good yields (see scheme).
Chem. Eur. J, 2011, DOI: 10.1002/chem.201101192
H activation process. In the presence of tert-butyl hydroperoxide (TBHP) as the ideal oxidant, this reaction provides an efficient access to ortho-acyl acetanilides in good yields (see scheme).Chem. Eur. J, 2011, DOI: 10.1002/chem.201101192
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