Easy access too-acyl acetanilides: A new Pd-catalyzed ortho-acylation of acetanilides with both aromatic and aliphatic aldehydes has been developed based on a C![[BOND]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_uNNzKL4x73XovxQNMWGOcRdCsOMNXmAXLA1aatONvdR9ADkqvSqd7DxqRJvVRRjd76kF8FlFipmizwRCycxCv0ivNqk1YxKNSlY300pVIiIejXGAzoBWgVdZkOQ41yavtH6kr0xGVq-j3KJA=s0-d)
H activation process. In the presence of tert-butyl hydroperoxide (TBHP) as the ideal oxidant, this reaction provides an efficient access to ortho-acyl acetanilides in good yields (see scheme).
Chem. Eur. J, 2011, DOI: 10.1002/chem.201101192
H activation process. In the presence of tert-butyl hydroperoxide (TBHP) as the ideal oxidant, this reaction provides an efficient access to ortho-acyl acetanilides in good yields (see scheme).Chem. Eur. J, 2011, DOI: 10.1002/chem.201101192
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