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Nature Chemistry

Sunday, August 7, 2011

Synthesis of 1-Aminoisoquinolines via Rh(III)-Catalyzed Oxidative Coupling

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[RhCp*Cl2]2 can catalyze the oxidative coupling of N-aryl and N-alkyl benzamidines with alkynes to give N-substituted 1-aminoisoquinolines in high selectivity.

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