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Wednesday, August 22, 2012

Pd-catalyzed double C–H bond activation of diaryl ketones for the synthesis of fluorenones

Graphical abstract: Pd-catalyzed double C–H bond activation of diaryl ketones for the synthesis of fluorenones

An efficient synthesis of fluorenones from diaryl ketones by Pd-catalyzed oxidative cyclization is described. A possible mechanism involving a carbonyl group assisted ortho-C–H activation and cyclometalation followed by a second C–H activation to form a six-membered palladacycle and reductive elimination is proposed.

Copper-Mediated Multiple C–H Functionalization of Aromatic N-Heterocycles: Bromoamination of Indoles and Pyrroles - Organometallics (ACS Publications)

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Palladium-Assisted Regioselective C–H Cyanation of Heteroarenes Using Isonitrile as Cyanide Source

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Room Temperature, Palladium-Mediated P–Arylation of Secondary Phosphine Oxides

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Room Temperature Copper(II)-Catalyzed Oxidative Cyclization of Enamides to 2,5-Disubstituted Oxazoles via Vinylic C–H Functionalization

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Conjugate Addition vs Heck Reaction: A Theoretical Study on Competitive Coupling Catalyzed by Isoelectronic Metal (Pd(II) and Rh(I))

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Palladium-Catalyzed Direct Arylation of 5-Chloropyrazoles: A Selective Access to 4-Aryl Pyrazoles - The Journal of Organic Chemistry (ACS Publications)

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A Mild, Palladium-Catalyzed Method for the Dehydrohalogenation of Alkyl Bromides: Synthetic and Mechanistic Studies

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Catalytic Intermolecular C-Alkylation of 1,2-Diketones with Simple Olefins: A Recyclable Directing Group Strategy

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Saturday, August 11, 2012

Oxidative Alkenylation of Aromatic Esters by Ruthenium-Catalyzed Twofold C–H Bond Cleavages

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Ruthenium-Catalyzed Oxidative C(sp2)–H Bond Hydroxylation: Site-Selective C–O Bond Formation on Benzamides

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Ru(II)-Catalyzed Amidation of 2-Arylpyridines with Isocyanates via C–H Activation

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Cobalt-Catalyzed Ortho-Arylation of Aromatic Imines with Aryl Chlorides

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Palladium(II)-Catalyzed Enantio- and Diastereoselective Synthesis of Pyrrolidine Derivatives

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An Asymmetric Organocatalytic Povarov Reaction with 2-Hydroxystyrenes

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Pd-Catalyzed Benzylic C–H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones

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Oxidative Coupling of Indoles with Ethyl 2-(Disubstituted Amino)Acetates: An Approach to Achieve Indolylglycine Derivatives

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Transition-Metal-Catalyzed Enantioselective Heteroatom–Hydrogen Bond Insertion Reactions

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Aromatic Interactions as Control Elements in Stereoselective Organic Reactions

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Palladium-Catalyzed Oxidation of Unsaturated Hydrocarbons Using Molecular Oxygen

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Palladium-Catalyzed C(sp3)–H Arylation of Diarylmethanes at Room Temperature: Synthesis of Triarylmethanes via Deprotonative-Cross-Coupling Processes

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Rh-Catalyzed Intermolecular Carbenoid Functionalization of Aromatic C–H Bonds by α-Diazomalonates

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Decarbonylative C–H Coupling of Azoles and Aryl Esters: Unprecedented Nickel Catalysis and Application to the Synthesis of Muscoride A - Journal of the American Chemical Society (ACS Publications)

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Carbon–Carbon Bond Formation: Palladium-Catalyzed Oxidative Cross-Coupling of N-Tosylhydrazones with Allylic Alcohols



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