Iodine(iii)-mediated construction of the dibenzoxazepinone skeleton from 2-(aryloxy)benzamides through oxidative C–N formation

DOI: 10.1039/C5RA20258B

Synthesis of Dibenzofurans via C–H Activation of o-Iodo Diaryl Ethers

Chemoselective Intramolecular Functionalization of Methyl Groups in Nonconstrained Molecules Promoted by N-Iodosulfonamides

DOI: 10.1021/acs.orglett.5b00866

Synthesis of Substituted Tetrahydron-1H-carbazol-1-one and Analogs via PhI(OCOCF3)2-Mediated Oxidative C-C Bond Formation

DOI: 10.1016/j.tet.2014.02.083

Steric Control of Site Selectivity in the Pd-Catalyzed C–H Acetoxylation of Simple Arenes

Iodine(III)-Promoted Synthesis of Oxazoles through Oxidative Cyclization of N-Styrylbenzamides

Hypervalent iodine(iii)-induced oxidative [4+2] annulation of o-phenylenediamines and electron-deficient alkynes: direct synthesis of quinoxalines from alkyne substrates under metal-free conditions

ortho-Acetoxylation of Phosphonic and Phosphoric Monoacids via Pd(II) Catalysis

Ruthenium-Catalyzed C–H Oxygenation on Aryl Weinreb Amides

Synthesis of Benzimidazoles by PIDA-Promoted Direct C(sp2)[BOND]H Imidation of N-Arylamidines

Synthesis of carbazolones and 3-acetylindoles via oxidative C–N bond formation through PIFA-mediated annulation of 2-aryl enaminones

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Intramolecular Oxidative Diamination and Aminohydroxylation of Olefins under Metal-Free Conditions

Org. Lett., 2012, DOI: 10.1021/ol300166q

A trans diacyloxylation of indoles

Chem. Commun., 2012, 48,             3239-3241  

Metal-Free Intermolecular Oxidative C–N Bond Formation via Tandem C–H and N–H Bond Functionalization

Brenton DeBoef, 2011, JACS DOI: 10.1021/ja2087085

A Metal-Free Route to 2-Aminooxazoles by Taking Advantage of the Unique Ring Opening of Benzoxazoles and Oxadiazoles with Secondary Amines

A Metal-Free Route to 2-Aminooxazoles by Taking Advantage of the Unique Ring Opening of Benzoxazoles and Oxadiazoles with Secondary Amines

Toss an amine into the ring: A new metal-free protocol for the amination of oxazoles has been developed by using iodobenzene diacetate to couple various oxazoles with amines (see scheme). The reaction proceeds through a ring-opening and subsequent ring-closing pathway. The optimal conditions are very mild and the substrate scope is broad, producing a range of 2-aminooxazoles, an important pharmacophore with high bioactivity.

 Prof. Dr. Sukbok Chang, Chemistry, 2011, DOI: 10.1002/chem.201100910