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Nature Chemistry

Monday, October 23, 2017

Ligand-Enabled γ-C(sp3)–H Cross-Coupling of Nosyl-Protected Amines with Aryl- and Alkylboron Reagents


Use of Electrochemistry in the Synthesis of Heterocyclic Structures


Three-Component Catalytic Carboxygenation of Activated Alkenes Enabled by Bimetallic Rh(III)/Cu(II) Catalysis


Rhodium-Catalyzed Direct Ortho C–H Arylation Using Ketone as Directing Group with Boron Reagent


Hydroxoiridium-Catalyzed Hydroarylation of Alkynes and Bicycloalkenes with N-Sulfonylbenzamides


Cobalt-Catalyzed Oxidative Cyclization of Benzamides with Maleimides: Synthesis of Isoindolone Spirosuccinimides

Iridium/Bipyridine-Catalyzed ortho-Selective C–H Borylation of Phenol and Aniline Derivatives


Rhodium-Catalyzed [4 + 3] Annulations of Sulfoximines with α,β-Unsaturated Ketones Leading to 1,2-Benzothiazepine 1-Oxides


Transition-Metal-Free C–CN/C–H Cross-Coupling: Effect of Cyano Group


Total Synthesis and Anti-inflammatory Evaluation of Penchinone A and Its Structural Analogues


Palladium-Catalyzed Direct C(sp2)–H ortho-Arylation of Anilides Using 2-Aminophenylpyrazole as the Directing Group


Monday, October 9, 2017

Visible-Light-Mediated Aerobic Oxidation of N-Alkylpyridinium Salts under Organic Photocatalysis


Carboxylate-Assisted Formation of Aryl-Co(III) Masked-Carbenes in Cobalt-Catalyzed C–H Functionalization with Diazo Esters


Manganese(I)-Catalyzed Direct C–H Allylation of Arenes with Allenes


Synthesis of 3-(2-Olefinbenzyl)-4H-chromen-4-one through Cyclobenzylation and Catalytic C–H Bond Functionalization Using Palladium(II)


Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination


Electrocatalytic Minisci Acylation Reaction of N-Heteroarenes Mediated by NH4I


Nickel(II)-Catalyzed Site-Selective C–H Bond Trifluoromethylation of Arylamine in Water through a Coordinating Activation Strategy


Transformable Sulfoximine Assisted One-Pot Double Annulation of Vinylic C–H Bonds with Unactivated Alkynes


Visible-Light-Mediated Construction of Pyrroloindolines via an Amidyl Radical Cyclization/Carbon Radical Addition Cascade: Rapid Synthesis of (±)-Flustramide B


Sunday, October 8, 2017

Ligand-Promoted Palladium-Catalyzed Aerobic Oxidation Reactions


Visible Light Photocatalysis Using a Commercially Available Iron Compound


Photoactivated Transition-Metal Triggers for Ambient Temperature Enediyne and Dienyne Cyclization: Ruthenium-η6-Naphthalene Complexes


Ruthenacyclopentanes as Intermediates in the Regio- and Stereoselective Linear Codimerization of N-Vinylamides with Electron-Deficient Alkenes


Nickel-Catalyzed Cross-Coupling Reaction of Aryl Sulfoxides with Arylzinc Reagents: When the Leaving Group is an Oxidant


Mechanistic and Synthetic Investigations on the Dual Selenium-π-Acid/Photoredox Catalysis in the Context of the Aerobic Dehydrogenative Lactonization of Alkenoic Acids


Controllable Sulfoxidation and Sulfenylation with Organic Thiosulfate Salts via Dual Electron- and Energy-Transfer Photocatalysis


Monday, October 2, 2017

Natural Products as Platforms To Overcome Antibiotic Resistance


Dehydrogenation of Alkanes and Aliphatic Groups by Pincer-Ligated Metal Complexes


Site-Selective C–H/C–N Activation by Cooperative Catalysis: Primary Amides as Arylating Reagents in Directed C–H Arylation


Direct Allylic C–H Bond Activation To Synthesize [Pd(η3-cin)(IPr)Cl] Complex: Application in the Allylation of Oxindoles



Visible-Light-Induced External Oxidant-Free Oxidative Phosphonylation of C(sp2)–H Bonds


Ketene Aminal Phosphates: Competent Substrates for Enantioselective Pd(0)-Catalyzed C–H Functionalizations


Cp*CoIII-Catalyzed Branch-Selective Hydroarylation of Alkynes via C–H Activation: Efficient Access to α-gem-Vinylindoles


Site-Selective Deuteration of N-Heterocycles via Iridium-Catalyzed Hydrogen Isotope Exchange


Micelle-Enabled Palladium Catalysis for Convenient sp2-sp3 Coupling of Nitroalkanes with Aryl Bromides in Water Under Mild Conditions


Mild and Efficient Ni-Catalyzed Biaryl Synthesis with Polyfluoroaryl Magnesium Species: Verification of the Arrest State, Uncovering the Hidden Competitive Second Transmetalation and Ligand-Accelerated Highly Selective Monoarylation


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