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Tuesday, July 12, 2011

Palladium-Catalyzed Selective Dehydrogenative Cross-Couplings of Heteroarenes

A nice couple: Two heteroaryls bearing no prefunctionalization can be cross-coupled efficiently through PdII catalysis to afford the biheteroaryl. The selectivity of this transformation probably finds its origin in the two mechanistically different metalation steps of C[BOND]H bonds.


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